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Drugmakers have brought almost 450 orphan drugs to market and collected rich incentives but nearly a third of those products aren鈥檛 new or were repurposed multiple times, an investigation shows.
Follow the twists and turns of the orphan drug industry over the past three decades.
Check out all the drugs the FDA has approved to treat rare diseases. You can search by brand name, or by disease, and see familiar names that were first sold on the mass market or all the drugs that won FDA approval to treat more than one rare disease.
The former Congressman championed the Orphan Drug Act decades ago but now he fears it鈥檚 being manipulated to make money.
The federal government pays for kidney transplants. But the program only pays for essential anti-rejection drugs for three years. Many people can't afford them and can end up losing the kidney.
Investigators claim drugmaker employees met in secret at restaurants, golf outings and at 鈥淕irls Night Out鈥 to raise generic drug prices.
Eight percent of those polled by the Kaiser Family Foundation say they have purchased medications outside of the U.S. to save money.
Advocates want alternatives to drugmaker's pricey pills for those who choose to die in Colorado and elsewhere.
Three lobbyists for every member of Congress in a push to pass a bill that increases research funding and speeds up approvals.
The legislation would give federal officials more flexibility in evaluating the effectiveness and safety of drugs and devices and add billions of dollars to NIH funding. But critics say it could endanger patients鈥 safety and doesn鈥檛 do enough to stop spiraling drug prices.
Despite heavy opposition from the pharmaceutical industry and skepticism from policy experts, many voters see Proposition 61 as a way to protest the nation鈥檚 mounting drug prices.
Majorities of Democrats, Republicans and independents support making sure high-cost drugs for chronic conditions are affordable.
Climbing drug prices are taking a toll on West Virginia's budget, some state legislators say. Expensive drugs fuel an increase in Medicaid spending, which leaves less money for schools and roads.
The plans sought to discourage costly HIV patients by not including their drug needs in formularies or requiring high cost sharing, a Harvard Law School group says in a complaint filed with HHS.
In a report out Tuesday, hospital groups said drug prices have skyrocketed since 2013, triggering a huge increase in what hospitals spend on pharmaceuticals.
KHN鈥檚 Julie Appleby joined forces with USA Today to create this chart, which details the various industry players and how they contribute to a prescription drug鈥檚 cost.
Ten-year-old Josh Hardy died last month. His struggle to survive helped to spur laws to get unapproved drugs to the terminally ill.
A voucher awarded to companies that find treatments for rare childhood diseases can be sold to the highest bidder 鈥 and then used to speed up approvals for much more common drugs.
Such medications account for more than a quarter of the state agency鈥檚 $2.1 billion in pharmacy costs.
The number of prescriptions for Medicare beneficiaries is on the rise, too.
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