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Morning Briefing

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Wednesday, Jun 14 2023

Full Issue

Demand For Antibiotic In Short Supply May Impact Sick Children Soon: Pfizer

Pfizer warned that supply of the pediatric version of its drug Bicillin L-A is expected to be exhausted by the end of this quarter. The adult formulation of the drug is in demand for treating a spike in syphilis infections. The pediatric version isn't widely used, though, Pfizer said.

Pfizer has warned that a drug used to treat syphilis and other bacterial infections in children could run out by the end of June because it has had to prioritize versions made for adults due to a spike in syphilis infections in that population. Supply of the pediatric version of the drug, Bicillin L-A, is expected to be exhausted by the end of this quarter, the company said in a letter to the U.S. health regulator dated Monday. Pfizer said in an email on Tuesday that the pediatric formulations of the antibiotic are not widely used. (6/13)

In other pharmaceutical news 鈥

Indian authorities have launched an inquiry into an allegation that a local pharmaceutical regulator, in return for a bribe, helped switch samples of cough syrups that the World Health Organization (WHO) had linked to the deaths of children in Gambia before the samples were tested at an Indian laboratory, according to two government officials and documents reviewed by Reuters. (Das, 6/13)

A single dose of the VLA1553 chikungunya virus vaccine candidate triggered neutralizing antibody production in 98.9% of recipients 28 days later, finds a phase 3 randomized, controlled trial published yesterday in The Lancet. Chikungunya is a mosquito-borne virus that causes periodic outbreaks of an illness featuring severe joint and muscle pain that can lead to chronic rheumatic (inflammatory) disease. (Van Beusekom, 6/13)

Diana Mansfield credits her life to a miracle drug. Since undergoing a kidney transplant at UCSF in 2001, Mansfield has received infusions of an immunosuppressant every two months that prevent her body from rejecting the organ. But the drug鈥檚 manufacturer, Bristol Myers Squibb, has cut back recently on聽funding聽for research on the medication, called belatacept, and now says it will halt investment entirely. It鈥檚 a blow to transplant patients and doctors hoping for improved regimens of the drug, and for inquiries into its use as a treatment for other ailments. (Castro-Root, 6/13)

The Ozempic weight-loss craze has fueled new interest in a dietary supplement with roots in ancient traditional medicine as a cheap way to shed pounds.聽Posts mentioning berberine, dubbed 鈥渘ature鈥檚 Ozempic,鈥 have racked up millions of views on the social network TikTok, where some people claim it can help with weight loss, as well as other ailments. ... In the U.S., it is available in the form of a pill or powder from a range of manufacturers, though like other supplements, it isn鈥檛 regulated by the U.S. Food and Drug Administration. (Subbaraman, 6/14)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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