�������ýҕ�l

Two federal panels of addiction experts on Wednesday unanimously recommended that Narcan, the overdose-reversing nasal spray, be made widely available without a prescription, a significant step in the effort to stem skyrocketing drug fatalities. Making Narcan an over-the-counter drug has been urged by doctors, patient advocacy groups and the Biden administration. (Hoffman, 2/15)

The positive vote, which is not binding, came despite concerns from some panel members about the drug’s instructions and packaging, which caused confusion among some people in a company study. The manufacturer, Emergent Biosolutions, said it would revise the packaging and labeling to address those concerns. The FDA will make a final decision on the drug in coming weeks. Panel members urged the FDA to move swiftly rather than waiting for Emergent to conduct a follow-up study with the easier-to-understand label. (Perrone, 2/15)

Two manufacturers are applying for nonprescription status: Emergent BioSolutions — the focus of Wednesday’s meeting — and Harm Reduction Therapeutics, a nonprofit organization. The FDA granted both companies a priority review and is likely to issue an approval decision within months. (Facher, 2/15)

“For the sake of the public and saving lives, I believe this medication should be available over the counter as soon as possible,” Dr. Katalin Roth, a professor of medicine at the George Washington University School of Medicine and Health Sciences, said following the vote. (Lovelace Jr., 2/15)

All states have standing orders that allow a person to get naloxone from a pharmacist without a doctor’s prescription, but consumers must approach a pharmacist and ask for the medication before purchasing. Dr. Bobby Mukkamala, chair of the American Medical Association's substance use and pain care task force, said a retail version of the drug would make it easier for people to access. “Making naloxone over the counter is a safe and vital step to ending the nation’s overdose epidemic," Mukkamala said.

In October, a new clinic offering opioid addiction treatment opened in Guilford County. Patients get connected to the clinic by the post-overdose response team at an organization called Guilford County Solution to the Opioid Problem — better known as GC STOP. Now, 48 people who overdosed in the community have been connected to treatment and medication thanks to the new initiative, which was made possible by a grant using funds from a massive legal settlement with McKinsey & Company. (Knopf, 2/16)

Colorado cities could let “overdose prevention centers,” where people would be allowed to openly use illicit drugs under the supervision of health care workers or other trained staff, operate within their boundaries under a bill introduced in the state legislature Wednesday by four Democrats. (Paul, 2/15)

New Jersey lawmakers are advancing a pair of bills that would toughen sentences for fentanyl possession and dealing, which advocates for people who use drugs fear could end up deterring people from reporting overdoses and punish people struggling with addiction. (Whelan, 2/16)

A record 193 homeless people died in Oregon’s Multnomah County, home to Portland, in 2021, a 53% increase compared with the previous year, according to a new county report released Wednesday. Substances contributed to about 60% of those deaths, the report found, mirroring trends seen across the country. (Rush, 2/15)