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Tuesday, Apr 21 2020

Full Issue

Perspectives: Hints That Remdesivir Works Against Coronavirus A Lot More Tenuous Than Investors Seem To Believe

Read recent commentaries about drug-cost issues.

The latest round of hype on Covid-19 drugs began Thursday afternoon when Stat News reported on a leaked video discussion about Gilead Sciences Inc鈥檚 remdesivir. A Chicago doctor who had tested it on severely ill patients suggested it was working 鈥 that most of those who were given the medicine recovered and were discharged. The market is reacting as if the drug were already a commercial hit: Gilead shares have been up as much as 12% in early trading.聽Investors聽should be clear about what this report is and isn鈥檛, however. It is a聽promising anecdote that suggests the drug might be useful. It is also extremely limited information from a small portion of a trial taken out of聽context. In other words, it鈥檚 miles from providing proof that remdesivir cures Covid-19. The story is even further from being a reasonable basis for a multibillion-dollar stock move. (Max Nisen, 4/17)

Things have gone from bad to worse for Brian Helstien. For a decade, he鈥檚 been grappling with multiple myeloma, a form of blood cancer. Now he needs surgery for a leaky heart valve. But because his medical network, Kaiser Permanente, like all healthcare providers, is dealing with a tsunami of COVID-19 patients, the Laguna Woods resident has been informed his non-life-threatening ticker trouble is an 鈥渆lective鈥 procedure. (David Lazarus, 4/21)

Make no mistake: The only long-term solution to the Covid-19 pandemic is a safe and effective vaccine. The current focus on identifying effective treatments, while important, serve only as a temporary Band-Aid. We don鈥檛 know yet if hydroxychloroquine, remdesivir, or any of the other repurposed drugs currently being tested in a blitzkrieg of quickly designed clinical trials are going to work and save lives. It鈥檚 highly likely that most of them, if not all of them, will fail or be only marginally helpful. (Stewart Lyman, 4/21)

When I started working in the biopharma industry 20 or so years ago, I didn鈥檛 think I would need to become an expert in crisis management. Yet during the past decade, I have found myself leading the corporate response to three very different existential crises in three different regions. Despite the unique aspects of each situation, they share important commonalities that shed some light on actions and attitudes that can help guide and improve corporate leaders鈥 response to the coronavirus pandemic, in the United States and globally. (Mahesh Karande, 4/20)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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