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Morning Briefing

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Tuesday, Aug 9 2022

Full Issue

Pfizer Begins Vaccine Trial To Combat Lyme Disease

The in-development drug, called VLA15 and designed in partnership with Valneva, will be tested on about 6,000 people internationally, including in the U.S. Pfizer is also in the news for a new drug warranty on CIPD drug Panzyga, and for buying Global Blood Therapeutics for $5.4 billion.

If proven safe and effective, the vaccine, currently called VLA15, could be an important tool to stop the tick-borne disease that affects聽nearly half a million Americans a year. Although many people clear the infection with a course of antibiotics, others suffer for years from lingering symptoms. (Weintraub, 8/8)

In other news from Pfizer 鈥

For only the second time, Pfizer is offering a warranty for a medicine that will cover the cost for any patient or health plan if the medication fails to work, a move that expands an effort to appease concerns about high drug costs. (Silverman, 8/8)

Pfizer 鈥 cash-rich thanks to its coronavirus vaccine 鈥 is bringing Global Blood Therapeutics into the fold under a $5.4 billion all-cash deal announced Monday. The acquisition of the maker of Oxbryta, one of the few treatments approved by the Food and Drug Administration for sickle cell disease, is the latest blockbuster deal for the pharmaceutical giant. (Gregg, 8/8)

In earnings updates from Novavax and BioNTech 鈥

Novavax Inc. slashed its full-year revenue outlook in half on Monday, citing a lack of demand for its Covid-19 vaccine from an international initiative to vaccinate lower-income countries and delays in winning expanded authorizations in the U.S. Novavax said Monday it now expects 2022 sales between $2 billion and $2.3 billion, down from its previous forecast of $4 billion to $5 billion.聽 (Walker, 8/8)

BioNTech, which teamed with Pfizer to develop a powerful COVID-19 vaccine, has reported higher revenue and net profit in the first half of the year and expects demand to grow as it releases updated vaccines to target new omicron strains. The German pharmaceutical company said Monday that revenue hit about 9.57 billion euros ($9.76 billion) in the first six months of 2022, up from nearly 7.36 billion euros in the same period a year earlier. (8/8)

In other news about medical research 鈥

KHN: 鈥楢merican Diagnosis鈥: 鈥榃e Need To Be At The Table鈥: Native-Led Medical Research Aims To Rebuild Trust聽

Mending broken trust may be a first step for investigators who want to increase the participation of Native people in medical research.聽鈥淭here鈥檚 such a history of extractive research in Indigenous communities, such that 鈥榬esearch鈥 and 鈥榮cience鈥 are sometimes dirty words,鈥 said Navajo geneticist and bioethicist Krystal Tsosie. (8/9)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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