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A blood test for detecting cancer early being developed by the diagnostics firm Grail failed to meet its main goal in a giant study being conducted with England’s National Health Service, the company said Thursday. (Herper and Chen, 2/19)

A novel single-tablet regimen (STR) combining the drugs bictegravir and lenacapavir provided similar viral suppression as multi-pill antiretroviral therapy among older adults with HIV, according to a phase 3 clinical trial published today in The Lancet. The STR also increased treatment satisfaction among participants for 48 weeks of follow-up, or about 11 months. (Bergeson, 2/25)

A large 9-year Korean study showed that current smoking status, not historical use, was the primary driver behind a reduced risk of Parkinson's disease. (George, 2/25)

University of Maryland researchers found that watching someone get relief from pain in a video can have pain-relieving effects. (Hille, 2/23)

A selective strategy for calcium supplementation after total thyroidectomy was just as safe and effective as blanket routine supplementation, and spared some patients from potentially unnecessary medication, a randomized trial showed. (Monaco, 2/19)