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Morning Briefing

Summaries of health policy coverage from major news organizations

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Wednesday, Apr 12 2023

Full Issue

Vaccination Centers Were Too Limited During Mpox Spread; 'Antibiotic Resistance Genes' Found In Food

Read about the biggest pharmaceutical developments and pricing stories from the past week.

A new study in JAMA Network Open shows that availability of the two-dose Jynneos vaccine to protect against mpox was not widespread during last summer's outbreak, with only 17.1% of the US population living within 15 minutes of a vaccination site and 50% living more than an hour away. (Soucheray, 4/11)

An analysis of prominent probiotic bacteria strains isolated from food and probiotic dietary supplements found the presence of several antibiotic resistance genes (ARGs), Hungarian researchers reported yesterday in Eurosurveillance. (Dall, 4/7)

Atopic dermatitis and psoriasis are well-established battlefields for anti-inflammatory biologic drugs. Now, two drugmakers are preparing to launch products in a lesser-known disease area with significant unmet medical need: hidradenitis suppurativa (HS). (Liu, 4/10)

A new drug, a monoclonal antibody known as enoblituzumab, is safe in men with aggressive prostate cancer and may induce clinical activity against cancer throughout the body, according to a phase 2 study. If confirmed in additional studies, enoblituzumab could become the first promising antibody-based immunotherapy agent against prostate cancer. (John Hopkins Medicine, 4/10)

U.S. neurologists are 鈥渃autiously optimistic鈥 about using Eisai鈥檚 Leqembi in Alzheimer鈥檚 disease as concerns about safety and the need for the FDA鈥檚 full green light for the drug remain high barriers to uptake. (Adams, 4/11)

AbbVie Inc and partner Johnson & Johnson intend to voluntarily withdraw the accelerated approvals of their Imbruvica drug in the U.S. for patients with certain types of blood cancer, the companies said on Thursday. (4/6)

Respiratory syncytial virus (RSV) infection causes considerable illness in older adults. The efficacy and safety of an investigational bivalent RSV prefusion F protein鈥揵ased (RSVpreF) vaccine in this population are unknown. (Walsh, M.D., et al, 4/5)

This is part of the Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.
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