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For local Harris County healthcare workers, Good Friday marked a milestone. The Harris Health System discharged its only COVID-19 patient from the Lyndon B. Johnson Hospital Friday afternoon, according to a tweet from the system's president and CEO Dr. Esmaeil Porsa. That gave the hospital zero COVID-19 patients for the first time since the start of the pandemic in March 2020, the health service stated. (Umanzor, 4/16)

A COVID-19 omicron variant hybrid called XE has been detected in Hawaii, the Hawaii state Department of Health said. The department’s laboratories division confirmed one case of XE in its latest variant report, the Honolulu Star-Advertiser reported Friday. The hybrid contains genetic material from both BA.1 and BA.2 variants. The department found it in a sample collected last month. (4/15)

As sub-variants of omicron continue to spread in the U.S. and abroad, infections are rising in East Coast states and cities. There were 54,543 new cases in the US. in the past day, according to the Johns Hopkins Coronavirus Resource Center. There were also 778 new deaths. 12,736 of those infections were in New York, Virginia reported nearly 1,100, 775 were in Maryland and the COVID-19 level in the District of Columbia was raised to "Medium" at the beginning of the month. (Musto, 4/15)

Reinfections account for about 9 percent of new COVID-19 cases reported in Nevada, according to state data, a growing number blamed in part on easily transmissible variants. This is triple the overall rate of 3 percent of cases since the beginning of the pandemic, according to data from the Nevada Department of Health and Human Services. “Since January, reinfections are a greater proportion of total infections,” said Dr. Marc Kahn, dean of the Kirk Kerkorian School of Medicine at UNLV. “And most of that is because of the infectivity of both omicron and the BA.2 variant.” (Hynes, 4/15)

The community transmission levels of COVID-19 have significantly increased throughout the state since last month, data released on Thursday by the U.S. Centers for Disease Control and Prevention show. This comes as wastewater data collected from several Maine cities show an increased presence of the virus, rivaling other major U.S. cities, according to Maine Center for Disease Control and Prevention data. Community transmission levels are high in Somerset, Aroostook, Penobscot, Washington, Waldo, Knox, Kennebec, Oxford, Cumberland, York and Sagadahoc counties, according to U.S. CDC data. (Stockley, 4/15)

Ohio Gov. Mike DeWine has tested positive for COVID-19. The 75-year-old Republican said in an announcement late Friday he was diagnosed by his personal physician after experiencing mild symptoms such as a runny nose, head ache, body aches and a sore throat. DeWine was administered a monoclonal antibody treatment, which is designed to fight the infection. He said he is following the U.S. Centers for Disease Control and Prevention protocol and quarantining. (Smyth, 4/15)

While most Americans are shedding their masks and returning to their pre-pandemic lives, Marie Jackson remains in a Chicago hospital room. She has been there for more than 250 days. There is no indication yet when Jackson, 53, will be able to go home. She's waiting on a new pair of lungs; hers were irreversibly scarred when she was sickened by Covid-19 last July. (Edwards, 4/16)

Covid-19 patients can harbor the coronavirus in their feces for months after infection, researchers found, stoking concern that its persistence can aggravate the immune system and cause long Covid symptoms. In the largest study tracking SARS-CoV-2 RNA in feces and Covid symptoms, scientists at California’s Stanford University found that about half of infected patients shed traces of the virus in their waste in the week after infection and almost 4% patients still emit them seven months later. The researchers also linked coronavirus RNA in feces to gastric upsets, and concluded that SARS-CoV-2 likely directly infects the gastrointestinal tract, where it may hide out. (Gale, 4/15)

Only 10% of household pets whose owners had Omicron came down with the virus and none were symptomatic, making them unlikely candidates to mutate and spread a more dangerous version of COVID, according to a new study released this week by Spanish researchers. ... Other studies have found that other COVID variants like Alpha and Delta were more easily transmitted to household pets, that infected pets were more likely to show symptoms, and that higher viral loads were detected in the pets, according to the study. (Prater, 4/16)

A history of certain psychiatric disorders may predispose fully vaccinated COVID-19 survivors to reinfection, according to a study of 263,697 US veterans published yesterday in JAMA Network Open. Researchers from the San Francisco Veterans Affairs (VA) Health Care System and the University of California retrospectively analyzed the administrative and electronic health records of US veterans who completed their COVID-19 vaccine primary series at least 14 days earlier from Feb 20, 2020, to Nov 16, 2021. Patients had received the Pfizer/BioNTech, Moderna, or Johnson & Johnson vaccine. (Van Beusekom, 4/15)

Rates of upper airway infections (UAIs) such as croup and bacterial tracheitis among pediatric COVID-19 patients, though low, rose after the Omicron variant became dominant in December 2021, with more than one fifth of hospitalized children with both conditions developing severe illness, estimates a study today in JAMA Pediatrics. (4/15)