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Vaccine-associated myocarditis shows a similar injury pattern on cardiac MRI compared to other causes of myocarditis, but abnormalities are less severe, according to a new study. (Radiological Society of North America, 2/15)

Older age is associated with poorer outcomes of SARS-CoV-2 infection, although the heterogeneity of ageing results in some older adults being at greater risk than others. The objective of this study was to quantify the association of a novel geriatric risk index, comprising age, modified Charlson comorbidity index, and Eastern Cooperative Oncology Group performance status, with COVID-19 severity and 30-day mortality among older adults with cancer. (Elkrief, M.D., et al, 2/14)

Researchers report the development of a versatile human nose organoid -- a laboratory representation of the cells layering the inside of the nose where the first events of a natural viral infection take place -- where they studied SARS-Cov-2 and RSV infections. (Baylor College of Medicine, 2/15)

Researchers have successfully used CRISPR-Cas9 to edit the genomes of the black-legged tick. To accomplish this feat, they developed an embryo injection protocol that overcame a major barrier in the field. (Cell Press, 2/15)

Tay–Sachs disease (TSD) is an inherited condition caused by mutations in the genes encoding β-hexosaminidase A (HexA), an enzyme responsible for the recycling of GM2 gangliosides, glycosphingolipids and oligosaccharides. Without this enzyme, these products accumulate in the lysosomes of nerve cells, among other cells, causing progressive neurodegeneration. (Timothy W. Yu and Olaf Bodamer, 2/10)

The brain's ability to clear a protein closely linked to Alzheimer's disease is tied to our circadian cycle, according to new research. The research underscores the importance of healthy sleep habits in preventing the protein Amyloid-Beta 42 (AB42) from forming clumps in the brain, and opens a path to potential Alzheimer's therapies. (Rensselaer Polytechnic Institute, 2/10)

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear. Now a new study confirms the health benefits of moderate calorie restrictions in humans -- and identifies a key protein that could be harnessed to extend health in humans. (Yale University, 2/10)

A new study shows how a particular molecule, produced by gut bacteria, affects brain function and promotes anxiety-like behaviors in mice. (California Institute of Technology, 2/14)